Related Experiment Video
Updated: Mar 15, 2026

Assessing Therapeutic Angiogenesis in a Murine Model of Hindlimb Ischemia
Published on: June 8, 2019
Potential of Using Occult Collateral Vessels for Transcollateral Intervention in Infrapopliteal Chronic Occlusion
Takashi Nakatsuji1, Osami Kawarada1, Teruo Noguchi1
1Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Insights
This study highlights using occult collateral vessels for transcollateral intervention in infrapopliteal chronic occlusion. This approach can reveal new treatment opportunities for critical limb ischemia patients.
Area of Science:
- Vascular surgery
- Interventional cardiology
- Endovascular techniques
Background:
- The transcollateral approach is a modern technique for treating chronic infrapopliteal artery occlusion.
- Critical limb ischemia with multilevel disease presents challenges in identifying all treatment pathways.
Observation:
- Angiographically occult collateral vessels, which are not readily visible on imaging, may be overlooked.
- These hidden vessels represent a potential, yet often missed, treatment opportunity.
Findings:
- This report demonstrates the potential of utilizing occult collateral vessels for transcollateral intervention.
- This technique can be applied to infrapopliteal chronic occlusions.
Implications:
- This strategy may expand treatment options for patients with complex infrapopliteal chronic occlusions.
- Identifying and utilizing occult collaterals could improve outcomes in critical limb ischemia management.
Abstract:
The transcollateral approach is a contemporary crossing technique for treating infrapopliteal chronic occlusion. However, in the setting of critical limb ischemia with multilevel disease, angiographically occult collateral vessels may be missed as a treatment opportunity. Herein, we report the potential of using occult collateral vessels for transcollateral intervention in infrapopliteal chronic occlusion.
More Related Videos
Related Concept Videos
Peripheral Artery Disease III: Interprofessional Care
Peripheral Artery Disease V: Postoperative Nursing Management

