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Related Experiment Videos

Cryotherapy for trichiasis in trachoma.

C D Rice1, R C Kersten, S al-Hazzaa

  • 1Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock 72205.

Archives of Ophthalmology (Chicago, Ill. : 1960)
|August 1, 1989
PubMed
Summary

Cryotherapy effectively treated trichiasis, a complication of trachoma, in Saudi Arabia. A second treatment significantly improved success rates, with hypopigmentation as the main side effect.

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Area of Science:

  • Ophthalmology
  • Tropical Medicine

Background:

  • Trichiasis, a common complication of trachoma, causes eyelid deformities.
  • Trachoma remains a leading cause of preventable blindness in endemic regions.

Purpose of the Study:

  • To evaluate the efficacy and safety of cryotherapy for treating trichiasis secondary to trachoma in Saudi Arabia.

Main Methods:

  • Cryotherapy using high-flow nitrous oxide was applied to 137 eyelids in a freeze-thaw-freeze cycle.
  • Treatment involved a 45-second application to the lid margin.

Main Results:

  • The initial success rate was 56%, increasing to 90% after a second treatment.
  • Hypopigmentation occurred in 8% of treated eyelids, primarily in highly pigmented individuals.

Conclusions:

  • Cryotherapy is a viable and effective treatment for trachoma-related trichiasis.
  • Its portability, cost-effectiveness, and ease of administration make it suitable for endemic areas.
  • Hypopigmentation is a notable complication in pigmented populations.

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