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[Biocompatibility and mechanical strength of various dura mater preparations after intraperitoneal implantation in
M Nagelschmidt1, B Bouillon, O Klinge
1Biochemische und Experimentelle Abteilung, Universität zu Köln.
Arzneimittel-Forschung
|May 1, 1989
Abstract:
Biocompatibility and mechanical strength of 3 different dura mater preparations were studied during 1, 2 and 4 weeks in a rat model. Two preparations produced by conventional methods did not markedly differ, whereas the third one, which had been freeze-dried after addition of glycerol, exhibited some special properties, showing higher mechanical strength throughout the whole period of implantation, and lower tendency to form adhesions, and inducing weaker leucocytic reaction. For certain surgical problems this soft, strong and compatible dura preparation could be an appropriate alternative.