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Coronary Artery Fistulas: Case Series and Literature Review
Christina Karazisi1, Peter Eriksson, Mikael Dellborg
1Section of Cardiology, Department of Medicine, Sahlgrenska University Hospital, Östra, Gothenburg, Sweden.
Insights
Congenital coronary artery fistulas are rare. Management is shifting from intervention to watchful waiting for asymptomatic patients due to potential post-closure complications.
Area of Science:
- Cardiology
- Congenital Heart Disease
Background:
- Congenital coronary artery fistulas (CCAFs) are uncommon cardiac anomalies.
- Increased accessibility of coronary angiography and multidetector computed tomography (MDCT) leads to more frequent diagnosis of CCAFs.
- CCAFs are often incidentally discovered during investigations for chest pain or heart failure.
Observation:
- Intervention via transcatheter or surgical closure is technically feasible for CCAFs.
- While many patients are asymptomatic immediately post-intervention, follow-up reveals potential sequelae.
- Reported complications include residual leakage, thrombosis, myocardial infarction, and coronary stenosis.
Findings:
- The natural history of CCAFs suggests a potential for spontaneous resolution or stable asymptomatic disease in some cases.
- Treatment outcomes highlight a trend towards conservative management in asymptomatic individuals.
- Evidence indicates that intervention, while possible, carries risks that may outweigh benefits in select patient groups.
Implications:
- The findings support a paradigm shift towards watchful waiting for incidental CCAFs in asymptomatic patients.
- This approach aims to mitigate risks associated with invasive procedures.
- Further research is needed to refine management guidelines and long-term surveillance strategies for CCAFs.
Abstract:
Congenital coronary artery fistulas are rare anomalies. As coronary angiography and multidetector computed tomography have become more accessible, they have been increasingly used in the investigation of chest pain and heart failure. Coronary artery fistulas are often an incidental finding, which raises the question of how patients with this condition should be managed. Intervention with either transcatheter closure or surgical closure is often technically possible. Many patients are asymptomatic early after closure. However, follow-up studies have shown post-closure sequelae, such as residual leakage, thrombosis with or without myocardial infarction, and coronary stenosis. Therefore, there has been a shift from intervention towards watchful waiting in asymptomatic patients. In this article, we review the published literature on the natural history and treatment outcomes in individuals with coronary artery fistulas. We present case reports from our clinic and discuss the management of incidental findings of coronary artery fistulas.
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