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Updated: Mar 15, 2026

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors
Published on: September 27, 2019
Classification of Itch
1Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany.
Abstract:
Chronic pruritus has diverse forms of presentation and can appear not only on normal skin [International Forum for the Study of Itch (IFSI) classification group II], but also in the company of dermatoses (IFSI classification group I). Scratching, a natural reflex, begins in response to itch. Enough damage can be done to the skin by scratching to cause changes in the primary clinical picture, often leading to a clinical picture predominated by the development of chronic scratch lesions (IFSI classification group III). An internationally recognized, standardized classification system was created by the IFSI to not only aid in clarifying terms and definitions, but also to harmonize the global nomenclature for itch.
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