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Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
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Basophil activation test: a reliable biomarker for allergen immunotherapy?
Polskie Archiwum Medycyny Wewnetrznej
|September 1, 2016
Abstract
No abstract available in PubMed .
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Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
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