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Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Acute generalized exanthematous pustulosis associated with spider bite
Laura de Mattos Milman1, Giana Paula Müller1, Paulo Ricardo Martins Souza1,2
1Complexo Hospitalar da Santa Casa de Misericórdia de Porto Alegre - Porto Alegre (RS), Brazil.
Abstract:
Acute generalized exanthematous pustulosis (AGEP) is an acute febrile rash, usually induced by drugs, which recently has been linked to spider bite. We report a case of a male patient, 48 years old, with an erythematous rash accompanied by fever and small non-follicular pustules. He reported previous pain in the buttock with the onset of a necrotic plaque. The lesion was compatible with spider bite of the genus Loxosceles. According to the EuroSCAR group instrument, the patient scored +10 indicating definite diagnosis of AGEP. As the patient had a compatible lesion and had no other triggers of AGEP, in an Loxosceles endemic area, the AGEP would be associated with spider bite, as described in other publications.
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