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Published on: March 12, 2020
Case for diagnosis. Metastatic Crohn's disease
João Renato Vianna Gontijo1, Franciele Antonieta Bianchi Leidenz1, Maria Silvia Laborne Alves de Sousa1,2
1Santa Casa de Misericórdia de Belo Horizonte Hospital, Belo Horizonte (MG), Brazil.
Metastatic Crohn's disease, a rare skin condition, presents as granulomatous lesions unrelated to the gut. This case highlights persistent skin papules and plaques in an adolescent with refractory Crohn's disease.
Area of Science:
- Dermatology
- Gastroenterology
- Pathology
Background:
- Crohn's disease (CD) is a chronic inflammatory bowel condition.
- Cutaneous manifestations affect up to 44% of CD patients.
- Metastatic CD is a rare skin manifestation characterized by granulomatous lesions histopathologically resembling bowel lesions.
Observation:
- A case of an adolescent patient with refractory Crohn's disease is presented.
- The patient exhibited persistent papules and plaques on the skin.
- These lesions were discontinuous from the gastrointestinal tract.
Findings:
- The skin lesions were diagnosed as metastatic Crohn's disease.
- Metastatic Crohn's disease represents the least common form of cutaneous manifestation in CD.
- Histopathological examination confirmed granulomatous inflammation consistent with CD.
Implications:
- This case underscores the importance of considering metastatic Crohn's disease in adolescents with refractory CD and unexplained skin lesions.
- Early recognition and diagnosis of metastatic Crohn's disease are crucial for appropriate management.
- Further research into the pathogenesis and treatment of this rare manifestation is warranted.
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