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Cognitive therapy, pioneered by Aaron T. Beck in the 1960s, is a structured approach to addressing psychological distress by focusing on the influence of thoughts on emotions and behaviors. All cognitive therapies involve the basic assumption that human beings have control over their feelings, and that how individuals feel about something depends on how they think about it. Unlike psychoanalytic methods that delve into unconscious processes or humanistic approaches emphasizing...
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Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
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Differential diagnosis, discerning depression from cognition.

E Portaccio1

  • 1Department of NEUROFARBA, University of Florence, Florence, Italy.

Acta Neurologica Scandinavica
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Cognitive impairment is common in multiple sclerosis (MS). While depression can worsen MS-related cognitive deficits, MS cognitive issues also exist independently of depression, suggesting a complex relationship.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Clinical Neurology

Background:

  • Cognitive impairment affects up to 70% of multiple sclerosis (MS) patients.
  • Depression is a common consequence of MS and a potential confounder in cognitive assessments.
  • Neurocognitive models suggest brain region dysfunction and connectivity issues contribute to mood disorders and cognitive strategies.

Purpose of the Study:

  • To explore the intricate relationship between cognitive function and depression in multiple sclerosis (MS).
  • To investigate whether depression causes or exacerbates cognitive impairment in MS patients.
  • To examine the potential for dysexecutive syndrome in MS to precipitate depression.

Main Methods:

  • Review of recent neuropsychiatric research and neurocognitive models.
  • Analysis of reported interplay between cognitive function and depression in MS.
  • Examination of depression's impact on attentional capacity, working memory, and executive control in MS.

Main Results:

  • Depression appears to alter attentional capacity, specifically impacting working memory and executive control in MS.
  • Cognitive impairment in MS can occur independently of depression.
  • Depression is more likely to exacerbate existing cognitive difficulties in MS than cause them directly.

Conclusions:

  • The relationship between cognitive impairment and depression in MS is complex and bidirectional.
  • While depression can worsen cognitive function in MS, cognitive deficits may also contribute to depression.
  • Further research is needed to fully elucidate the interplay between cognitive function, depression, and MS pathophysiology.