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An Integrative Analysis of microRNA and mRNA Profiling in CML Stem Cells
Farah J Nassar1, Rabab El Eit2, Rihab Nasr3
1Department of Biology, Faculty of Arts and Sciences, American University of Beirut, Beirut, Lebanon.
Methods in Molecular Biology (Clifton, N.J.)
|September 2, 2016
Abstract:
Integrative analysis of microRNA (miRNA) and messenger RNA (mRNA) in Chronic Myeloid leukemia (CML) stem cells is an important technique to study the involvement of miRNA and their targets in CML stem cells self-renewal, maintenance, and therapeutic resistance. Here, we describe a simplified integrative analysis using Ingenuity Pathway Analysis software after performing proper RNA extraction, miRNA and mRNA microarray and data analysis.
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