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Brain temperature could affect neurochemical evaluations
1In-Vivo Electrophysiology Unit; Behavioral Neuroscience Branch; National Institute on Drug Abuse - Intramural Research Program; National Institutes of Health; Baltimore, MD USA.
Abstract:
This article demonstrates the importance of natural brain temperature fluctuations as a critical factor affecting electrochemical detection of extracellular glutamate in awake rats and proposes a viable strategy to exclude this inescapable influence, thereby increasing the reliability of electrochemical measurements of glutamate in behaving animals.
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