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Related Concept Videos

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The human body is a powerhouse of energy, with every cell performing numerous functions that require energy. This energy production and consumption is measured by the metabolic rate, which quantifies the total heat generated by all the body's chemical reactions and mechanical work. This measurement helps to determine the rate of kilocalorie (kcal) consumption needed to fuel all ongoing activities.
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Temperature-Dependent Growth of Brook TroutThe growth of brook trout is closely influenced by water temperature. Experimental data demonstrate how trout weight changes over a 24-day period in response to varying water temperatures. At lower temperatures, such as 15.5 degrees Celsius, brook trout show significant weight gain. However, as the temperature increases, the amount of weight gained steadily decreases. At the highest temperature measured, 24.4 degrees Celsius, trout experience a net...
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Metabolic States of the Body: The Postabsorptive State01:18

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The postabsorptive state usually starts about four hours after a meal and lasts until the next meal is eaten. During this time, the digestive system stops absorbing nutrients, and the body uses stored energy reserves to maintain stable blood glucose levels.
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Energy Balance01:19

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The human body gets energy from the three macronutrients: carbohydrates, proteins, and fats. Energy is released when the chemical bonds in the organic compounds present in the food are broken down. The energy content of food is measured in kilocalories (kcal), defined as the amount of heat required to raise the temperature of one kilogram of water by one degree Celsius. This value is determined by measuring the temperature change of the water surrounding a calorimeter after the complete...
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Regulation of Metabolism01:19

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Cellular needs and conditions vary from cell to cell and change within individual cells over time. For example, the required enzymes and energetic demands of stomach cells are different from those of fat storage cells, skin cells, blood cells, and nerve cells. Furthermore, a digestive cell works much harder to process and break down nutrients during the time that closely follows a meal compared with many hours after a meal. As these cellular demands and conditions vary, so do the amounts and...
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Updated: Mar 15, 2026

Determining Basal Energy Expenditure and the Capacity of Thermogenic Adipocytes to Expend Energy in Obese Mice
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Does basal metabolic rate predict weight gain?

Pimjai Anthanont1, Michael D Jensen2

  • 1Endocrine Research Unit, Mayo Clinic, Rochester, MN.

The American Journal of Clinical Nutrition
|September 2, 2016
PubMed
Summary
This summary is machine-generated.

Adults with a low basal metabolic rate (BMR) do not gain more weight than those with a high BMR. This suggests that lifestyle factors like diet and activity balance out BMR differences in weight gain.

Keywords:
Western populationbody compositionbody-weight changeclinical researchenergy expenditurefree-living adultsindirect calorimetrylongitudinal follow-upobesity

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Area of Science:

  • Metabolism and Human Physiology
  • Obesity Research
  • Preventive Medicine

Background:

  • Previous research suggested a low basal metabolic rate (BMR) predicts future weight gain.
  • However, limited follow-up and specific populations in prior studies restricted generalizability.

Purpose of the Study:

  • To investigate if adults with a low BMR gain more weight than those with a high BMR in a typical Western environment.
  • To assess the predictive value of BMR on weight gain in a general adult population.

Main Methods:

  • Data from 757 weight-stable volunteers (1995-2012) were analyzed, including BMR, body composition, and demographics.
  • Volunteers were categorized into high and low BMR groups (top/bottom 15th percentile), adjusted for fat-free mass, fat mass, age, and sex.
  • Subsequent weight changes over approximately 9.7 years were tracked for 163 subjects.

Main Results:

  • The high-BMR group averaged 2001 ± 317 kcal/d, while the low-BMR group averaged 1510 ± 222 kcal/d.
  • Both groups were comparable in age, BMI, fat-free mass, and fat mass.
  • Weight gain rates were similar: 0.5 ± 1.5 kg/y in the high-BMR group versus 0.3 ± 1.0 kg/y in the low-BMR group (P=0.17).

Conclusions:

  • Low BMR did not correlate with greater weight gain in adults compared to high BMR.
  • Habitual differences in food intake or physical activity likely counterbalance BMR variations as a weight gain risk factor in Western populations.