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Potassium concentration influences the gating of K+ channels from sarcoplasmic reticulum
1Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Brasil.
Abstract:
Gating of K+ channels from the sarcoplasmic reticulum (SR) is influenced by the K+ concentration in the bathing solution. The probability of finding the channel open (Po) increases nonlinearly with the K+ concentration. The current two-state model which considers only voltage-dependent rate constants for the SR K+ channel should be reconsidered in the light of the present results.