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Effect of vitamin E on red blood cell preservation
M S Leonart1, A M Weffort-Santos, E M Muñoz
1Departamento de Patologia Médica, Universidade Federal do Paraná, Curitiba, Brasil.
Abstract:
The effect of exogenous vitamin E (2.1 mg/100 ml) was determined on the preservation of red blood cell integrity (PCV and RBC counts) during long-term storage. Cells from healthy human blood donors, normal rats and rats raised on a vitamin E-deficient diet were stored in CE medium at 4 degrees C for 40-60 days. The addition of vitamin E to the CE medium protected normal rat RBC and those from vitamin E-deficient animals to even a larger extent. Neither the PVC nor RBC count in human blood changed during storage for up to 60 days and no effect of exogenous vitamin E was demonstrable.