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Hypercalcaemia causing declining cognitive function in a head injured patient.

G Seliger1, F Cosman, G M Abrams

  • 1Department of Neurology, Columbia University.

Brain Injury
|July 1, 1989
PubMed
Summary
This summary is machine-generated.

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Hypercalcemia, or high blood calcium, is rare in immobilized adults. This case highlights its occurrence in a head-injured patient, leading to cognitive decline, emphasizing the need for calcium monitoring post-injury.

Area of Science:

  • Neurology
  • Endocrinology
  • Metabolic Disorders

Background:

  • Hypercalcemia is common in immobilized children but rare in adults without bone disease.
  • Immobilized adult patients typically do not develop hypercalcemia unless they have underlying bone conditions.

Observation:

  • A previously healthy, immobilized adult with a head injury developed hypercalcemia five months post-injury.
  • The patient experienced cognitive decline attributed to elevated calcium levels, exacerbated by mild dehydration from interrupted enteral feedings.

Findings:

  • Bone turnover indices were elevated, with suppressed parathyroid hormone, indicating a non-parathyroid source of hypercalcemia.
  • Severe immobilization and high pre-injury athletic activity may predispose to hypercalcemia in head-injured patients.

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Implications:

  • This case underscores the potential for hypercalcemia in immobilized head-injured adults, even months after the initial injury.
  • Close monitoring of fluid balance and serum calcium levels is crucial for managing head-injured patients to prevent complications like hypercalcemia.