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A Multicenter Retrospective Case Study of Anaphylaxis Triggers by Age in Korean Children

So Yeon Lee1, Kangmo Ahn2, Jihyun Kim2

  • 1Department of Pediatrics, Hallym University College of Medicine, Seoul, Korea.

Allergy, Asthma & Immunology Research
|September 2, 2016
PubMed

Insights

Food allergies are the leading cause of anaphylaxis in Korean children. Triggers vary by age, with milk common in younger children and seafood in older ones.

Area of Science:

  • Pediatric Allergy
  • Immunology
  • Public Health

Background:

  • Anaphylaxis is a severe, life-threatening allergic reaction.
  • Understanding anaphylaxis triggers is crucial for prevention and management.
  • Limited data exist on age-specific anaphylaxis triggers in pediatric populations.

Purpose of the Study:

  • To identify and analyze anaphylaxis triggers in Korean children.
  • To investigate age-specific patterns in anaphylaxis causation.

Main Methods:

  • Retrospective review of medical records for pediatric anaphylaxis cases.
  • Data collected from 23 secondary or tertiary hospitals in South Korea (2009-2013).
  • Analysis of anaphylaxis triggers based on patient age.

Main Results:

  • Food was the most frequent trigger (74.7%), followed by drugs/radiocontrast media (10.7%).
  • Milk was the most common food allergen in younger children; seafood in older children.
  • Drug-induced anaphylaxis increased with age, with antibiotics being a primary cause.

Conclusions:

  • Food is the predominant anaphylaxis trigger in Korean children.
  • Anaphylaxis triggers demonstrate significant variation across different age groups.
  • Age-specific data are essential for targeted anaphylaxis prevention strategies.
Abstract

Keywords:
Anaphylaxischildrenepidemiology

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