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Epidemiologic Analysis of Diverticulitis.

Marie D Jena1, Peter W Marcello1, Patricia L Roberts1

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Summary

Geographic analysis reveals significant variations in diverticulitis incidence across the US. High rates correlate with factors like tooth loss, suggesting potential links between dental health and diverticulitis burden.

Keywords:
BRFSSCDCdiverticulitisepidemiologypopulationseasonal variation

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Area of Science:

  • Gastroenterology
  • Epidemiology
  • Public Health

Background:

  • Diverticulitis incidence and geographic distribution in the US are not fully understood.
  • Behavioral and environmental factors may influence diverticulitis rates.

Purpose of the Study:

  • To evaluate geographic variation in diverticulitis incidence across the United States.
  • To examine behavioral and environmental factors associated with high diverticulitis rates.

Main Methods:

  • Utilized state hospital discharge data from 20 states (2002-2004).
  • Merged county-level diverticulitis data with Behavioral Risk Factor Surveillance System (BRFSS) data.
  • Analyzed associations between factors (e.g., tooth loss, smoking, sun exposure) and diverticulitis rates.

Main Results:

  • Recorded 345,216 hospitalizations for acute diverticulitis across 1,055 counties.
  • Diverticulitis rates varied widely, from 35.4 to 332.7 per 100,000 population.
  • High diverticulitis burden significantly associated with regions experiencing substantial tooth loss due to dental disease (p=0.0001).

Conclusions:

  • Considerable geographic variability exists in diverticulitis cases nationwide.
  • Tooth loss and potentially sun exposure emerge as potential triggers for diverticulitis.
  • Further research is warranted to elucidate the complex relationship between environmental/behavioral factors and diverticulitis.