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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Treatment of Metastatic Prostate Cancer in Older Adults
Kah Poh Loh1, Supriya G Mohile2, Elizabeth Kessler3
1James P Wilmot Cancer Institute, School of Medicine and Dentistry, University of Rochester, 601 Elmwood Avenue, Box 704, Rochester, NY, 14642, USA. kahpoh_loh@urmc.rochester.edu.
Abstract:
The aging of the population, along with rising life expectancy, means that increasing numbers of older men will be diagnosed with prostate cancer, and a large proportion of these men will present with metastatic disease. In this paper, we discuss recent advances in prostate cancer treatment. In particular, we review management approaches for older patients with metastatic prostate cancer based on the decision tree developed by the International Society of Geriatric Oncology, which categorized older men as "fit," "vulnerable," and "frail" according to comprehensive geriatric assessment.
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