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Health disparities in infants with hypertrophic pyloric stenosis

Alexander Feliz1, Janette L Holub2, Nima Azarakhsh2

  • 1Departments of Surgery and Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA.

American Journal of Surgery
|September 3, 2016
PubMed

Insights

Infants with hypertrophic pyloric stenosis (HPS) who are African-American or lack insurance face greater risks of metabolic issues and longer hospital stays, indicating health disparities in HPS care.

Area of Science:

  • Pediatric Surgery
  • Health Disparities Research
  • Neonatal Care

Background:

  • Hypertrophic pyloric stenosis (HPS) is a common surgical condition in infants.
  • Existing research suggests potential health disparities in HPS diagnosis and treatment.
  • This study aims to explore these disparities and their impact on infant outcomes.

Purpose of the Study:

  • To investigate health disparities in infants diagnosed with hypertrophic pyloric stenosis (HPS).
  • To identify socioeconomic and demographic factors influencing HPS treatment.
  • To assess the association between these factors and infant morbidity.

Main Methods:

  • Retrospective analysis of 584 infants with HPS over six years.
  • Statistical evaluation using ANOVA and general linear models.
  • Assessment of socioeconomic factors, race, insurance status, and clinical outcomes.

Main Results:

  • African-American infants exhibited distinct electrolyte abnormalities (lower chloride, higher bicarbonate and sodium) compared to white infants.
  • Uninsured infants showed similar electrolyte imbalances and a delayed time to operation.
  • These disparities were significantly associated with prolonged hospitalizations and metabolic derangements.

Conclusions:

  • Health disparities exist for African-American and uninsured infants with HPS.
  • These infants are at higher risk for metabolic derangements, requiring extended correction of dehydration and electrolytes.
  • Socioeconomic factors significantly impact HPS management and contribute to increased hospital stay duration.
Abstract

Keywords:
EthnicityHealth disparitiesHypertrophic pyloric stenosisRaceSocioeconomic status

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