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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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MRM Microcoil Performance Calibration and Usage Demonstrated on Medicago truncatula Roots at 22 T

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Technical Note: Experimental results from a prototype high-field inline MRI-linac.

G P Liney¹, B Dong², J Begg³

¹Department of Medical Physics, Ingham Institute for Applied Medical Research, Liverpool NSW 2170, Australia; Radiation Physics, Liverpool Cancer Therapy Centre, Liverpool NSW 2170, Australia; School of Medicine, University of New South Wales, Sydney NSW 2170, Australia; and Centre for Medical Radiation Physics, University of Wollongong, NSW 2522, Australia.

Medical Physics

|September 3, 2016

Summary

This summary is machine-generated.

This study demonstrates a functional high-field inline magnetic resonance imaging-linear accelerator (MRI-linac) system. The prototype shows feasibility for real-time image-guided radiotherapy, with image quality maintained during treatment delivery.

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Area of Science:

Medical Physics
Radiotherapy Technology
Medical Imaging

Background:

Real-time image-guided radiotherapy requires optimal tissue contrast.
Hybrid magnetic resonance imaging (MRI)-treatment systems are advancing radiotherapy.
Integrating MRI with linear accelerators (linacs) enables novel treatment delivery.

Purpose of the Study:

To demonstrate the feasibility of a high-field inline MRI-linac system.
To investigate image quality and technical challenges in a coupled MRI-linac.
To characterize a prototype experimental inline MRI-linac system.

Main Methods:

A 1.5 T MRI system was integrated with a linear accelerator in an inline configuration.
Experiments evaluated image quality using an ex vivo phantom with the radiation beam on/off.
Noise levels and electron contamination effects were measured using specialized equipment.

Main Results:

Image quality remained unaffected by the radiation beam.
A 25% elevation in background noise was observed with the radiation beam on.
Electron focusing along the magnet axis was confirmed.

Conclusions:

A proof-of-concept high-field inline MRI-linac was successfully built and characterized.
The system demonstrated efficacy for potential real-time image-guided radiotherapy.
Technical challenges and solutions for MRI-linac systems were investigated.