Related Experiment Videos
Felty's syndrome without concomitant arthritis: a variant
Z Cycowitz1, I Heller, M Burke
1Department of Medicine A, Tel Aviv Medical Center, Israel.
Clinical and Experimental Rheumatology
|May 1, 1989
Summary
This case report details a young woman with rheumatoid arthritis who developed severe neutropenia after treatment with aspirin, diclofenac, and gold salts. She responded well to prednisone, suggesting an unusual Felty
Area of Science:
- Rheumatology
- Hematology
- Clinical Case Study
Background:
- Rheumatoid arthritis (RA) is a chronic autoimmune disease.
- Felty's syndrome is a rare complication of RA characterized by rheumatoid arthritis, splenomegaly, and neutropenia.
- Drug-induced neutropenia can occur in patients with RA treated with various medications.
Observation:
- A young female patient with seropositive rheumatoid arthritis, previously treated with aspirin, diclofenac, and gold salts, presented with severe neutropenia.
- Clinical examination revealed fever, positive rheumatoid factor, and reversible swan-neck finger deformities, with otherwise normal joint findings.
Findings:
- The patient's severe neutropenia and associated symptoms were successfully managed with prednisone therapy.
- The presentation suggests an atypical manifestation of Felty's syndrome.
Implications:
- This case highlights the importance of considering unusual variants of Felty's syndrome in rheumatoid arthritis patients with neutropenia.
- Early recognition and appropriate treatment, such as with corticosteroids, can lead to favorable outcomes.