Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mass Spectrometers01:16

Mass Spectrometers

10.1K
This lesson details the instrumentation of a mass spectrometer—a physical instrument to perform mass spectrometry on analyte molecules and record the characteristic mass spectra. This is achieved via three chief functions:
10.1K
Tandem Mass Spectrometry01:21

Tandem Mass Spectrometry

2.8K
Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and reduce chemical noise during analyte detection. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called...
2.8K
Mass Spectrum: Interpretation01:24

Mass Spectrum: Interpretation

3.8K
An unknown compound can be established by identifying the molecular ion peak in the mass spectrum. The molecular ion peak is often weak or absent due to the predominance of fragmentation in high-energy electron beams. In such cases, a soft-energy electron beam can be used to scan the spectrum to enhance the intensity of the molecular ion peak. Additionally, chemical ionization, field ionization, and desorption ionization spectra are used to obtain a relatively intense molecular ion peak.To...
3.8K
Mass Analyzers: Overview01:13

Mass Analyzers: Overview

2.0K
The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...
2.0K
MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

7.4K
Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
7.4K
Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

1.8K
The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sequential application of Time of Flight-Secondary Ion Mass Spectrometry after vacuum metal deposition on glass, polyethylene terephthalate and polyvinyl chloride.

Science & justice : journal of the Forensic Science Society·2025
Same author

Exsolution of Fe-based pyramidal nanostructures from a noble metal doped perovskite matrix.

Nanoscale advances·2025
Same author

Boron-Functionalized Graphitic Carbon Nitride Materials for Photocatalytic Applications: Effects on Chemical, Adsorptive, Optoelectronic, and Photocatalytic Properties.

ACS materials Au·2025
Same author

Evidence of High Fluorine Ion Conductivity in SrF<sub>2</sub>-Rich SrF<sub>2</sub>-TiO<sub>2</sub>-Based Compounds.

ACS omega·2025
Same author

Ag-Ce<sub>0.9</sub>Gd<sub>0.1</sub>O<sub>2-δ</sub>-Based Nanocomposite Thin Film Air Electrodes for Low-Temperature Solid Oxide Cells.

ACS applied energy materials·2025
Same author

A Step-by-Step Design Strategy to Realize High-Performance Lithium-Sulfur Batteries.

ACS applied energy materials·2025

Related Experiment Video

Updated: Mar 15, 2026

Molecular Beam Mass Spectrometry With Tunable Vacuum Ultraviolet VUV Synchrotron Radiation
09:53

Molecular Beam Mass Spectrometry With Tunable Vacuum Ultraviolet VUV Synchrotron Radiation

Published on: October 30, 2012

13.7K

Note: A versatile mass spectrometer chamber for molecular beam and temperature programmed desorption experiments.

James P Tonks1, Ewan C Galloway2, Martin O King2

  • 1Department of Mechanical Engineering Sciences, University of Surrey, Guildford, Surrey GU2 7XH, United Kingdom.

The Review of Scientific Instruments
|September 3, 2016
PubMed
Summary

A novel mass spectrometer chamber design enables both molecular beam scattering (MBS) and temperature programmed desorption (TPD) with optimized performance. This versatile system enhances signal and angular resolution for surface science research.

More Related Videos

Spatial Separation of Molecular Conformers and Clusters
10:37

Spatial Separation of Molecular Conformers and Clusters

Published on: January 9, 2014

11.8K
Analysis of Volatile and Oxidation Sensitive Compounds Using a Cold Inlet System and Electron Impact Mass Spectrometry
05:48

Analysis of Volatile and Oxidation Sensitive Compounds Using a Cold Inlet System and Electron Impact Mass Spectrometry

Published on: September 5, 2014

10.1K

Related Experiment Videos

Last Updated: Mar 15, 2026

Molecular Beam Mass Spectrometry With Tunable Vacuum Ultraviolet VUV Synchrotron Radiation
09:53

Molecular Beam Mass Spectrometry With Tunable Vacuum Ultraviolet VUV Synchrotron Radiation

Published on: October 30, 2012

13.7K
Spatial Separation of Molecular Conformers and Clusters
10:37

Spatial Separation of Molecular Conformers and Clusters

Published on: January 9, 2014

11.8K
Analysis of Volatile and Oxidation Sensitive Compounds Using a Cold Inlet System and Electron Impact Mass Spectrometry
05:48

Analysis of Volatile and Oxidation Sensitive Compounds Using a Cold Inlet System and Electron Impact Mass Spectrometry

Published on: September 5, 2014

10.1K

Area of Science:

  • Surface Science
  • Analytical Chemistry
  • Physical Chemistry

Background:

  • Molecular Beam Scattering (MBS) and Temperature Programmed Desorption (TPD) are key surface analysis techniques.
  • Existing systems are often specialized for either MBS or TPD, limiting versatility.
  • Optimizing signal and resolution requires distinct experimental configurations.

Purpose of the Study:

  • To present a dual-purpose mass spectrometer chamber design.
  • To enable simultaneous optimization for both MBS and TPD techniques.
  • To demonstrate enhanced performance compared to single-purpose systems.

Main Methods:

  • Designing a mass spectrometer chamber with a variable entrance aperture diameter.
  • Implementing radial translation capability for the mass spectrometer chamber.
  • Systematically evaluating performance for both MBS and TPD.

Main Results:

  • The variable aperture allows for maximized signal in TPD or angular resolution in MBS.
  • Radial translation enables optimal positioning for signal maximization or angular resolution.
  • The dual-purpose system performance is comparable to dedicated MBS or TPD instruments.

Conclusions:

  • The developed mass spectrometer chamber offers a versatile and efficient solution for surface analysis.
  • This design integrates MBS and TPD capabilities without compromising performance.
  • The adaptability of the system makes it valuable for surface science research.