Related Experiment Video
Updated: Mar 15, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
Published on: December 10, 2016
Draft Genome Sequence of Clostridium difficile Belonging to Ribotype 018 and Sequence Type 17
E Riccobono1, V Di Pilato2, N Della Malva1
1Department of Experimental and Clinical Medicine, University of Florence, Careggi University Hospital, Florence, Italy.
The genome of Clostridium difficile ribotype 018 (RT018) strain CD8-15 was sequenced. This strain was isolated from a fatal case of C. difficile-associated infection in Italy.
Area of Science:
- Microbiology
- Genomics
- Infectious Diseases
Background:
- Clostridium difficile ribotype 018 (RT018) is a prevalent genotype in Italian hospitals.
- Clostridium difficile-associated infections (CDIs) can be severe and fatal.
Purpose of the Study:
- To report the draft genome sequence of C. difficile RT018 strain CD8-15.
- To provide genomic data for a strain isolated from a fatal CDI case.
Main Methods:
- Whole-genome sequencing of C. difficile strain CD8-15.
- Bioinformatic analysis of the resulting draft genome.
Main Results:
- The draft genome sequence of C. difficile RT018 strain CD8-15 was successfully generated.
- Genomic data provides insights into a prevalent Italian RT018 strain.
Conclusions:
- The availability of this genome sequence contributes to understanding C. difficile RT018.
- This data can aid in future research on C. difficile epidemiology and pathogenesis.
More Related Videos
09:44Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing
Published on: December 23, 2022
12:58A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
Published on: May 25, 2017
Related Concept Videos
Bacterial Phylum Tenericutes
Bacterial Phylum Firmicutes
Genomic DNA in Prokaryotes
Genomic Diversity in Bacteria
Although bacterial genomes are much...
Stringent Response in E. coli
Modern Molecular Taxonomy
Bacterial Phylum Proteobacteria