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Structure-oriented substrate specificity engineering of aldehyde-deformylating oxygenase towards aldehydes carbon

Luyao Bao1, Jian-Jun Li2, Chenjun Jia3

  • 1Key Laboratory of Biofuels, Chinese Academy of Sciences, Qingdao, China ; University of Chinese Academy of Sciences, Beijing, 100049 China.

Biotechnology for Biofuels
|September 3, 2016
PubMed
Summary

Researchers engineered aldehyde-deformylating oxygenase (ADO) to improve fatty alkane production. Mutants showed altered chain-length specificity, enabling targeted fuel property development.

Keywords:
Aldehyde-deformylating oxygenaseChain-length selectivitySite-directed mutagenesisStructure-guided protein engineeringSynechococcus elongatus PCC7942

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