Polymer therapeutics in surgery: the next frontier

Area of Science:

• Nanomedicine
• Polymer Science
• Surgical Innovation

Background:

• Polymer therapeutics are established in clinical practice but underutilized in perioperative care.
• Lack of literature exists on polymer therapeutics' application, safety, and potential for surgical patients.
• This study bridges this gap by reviewing the field's relevance to clinical surgery.

Approach:

• Overview of polymer therapeutics' evolution and demand-driven development.
• Exploration of cutting-edge concepts, implications, and limitations.
• Illustration with current clinical products and future developments.

Key Points:

• Design of polymer therapeutics influences biophysical and biochemical properties.
• Potential for targeted delivery and smart release mechanisms.
• Emphasis on safety and application in current surgical needs.

Conclusions:

• Surgeons need exposure to polymer therapeutics to maximize benefits.
• Fostering clinician-scientists is crucial for innovation in this field.
• Polymer therapeutics offer significant potential for advancing surgical practice.