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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
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Optic disc area in different types of glaucoma.
Oya Tekeli1, Esra Savku2, Ahmed Abdullayev1
1Department of Ophthalmology, Faculty of Medicine, Ankara University, Ankara 06590, Turkey.
International Journal of Ophthalmology
|September 3, 2016
Summary
Optic disc size influences retinal nerve fiber layer thickness in primary open-angle glaucoma. Larger optic disc area may be a risk factor for glaucomatous optic nerve damage.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Optic Nerve Imaging
Background:
- Glaucoma is a leading cause of irreversible blindness.
- Optic nerve damage is a hallmark of glaucoma.
- Understanding factors influencing optic nerve structure is crucial for early detection and management.
Purpose of the Study:
- To investigate the relationship between optic disc area and retinal nerve fiber layer (RNFL) thickness.
- To compare these parameters across different glaucoma subtypes and healthy controls.
Main Methods:
- Retrospective analysis of optical coherence tomography (OCT) data from patients with ocular hypertension, primary open-angle glaucoma (POAG), pseudoexfoliation glaucoma (PXG), and healthy controls.
- Measurements included optic disc area and circumpapillary RNFL thickness.
- Central corneal thickness was also assessed.
Main Results:
- Patients with POAG had a significantly larger median optic disc area compared to those with ocular hypertension.
- RNFL thickness was thinner in POAG and PXG patients than in ocular hypertension patients.
- In POAG, greater optic disc area correlated with thicker RNFL in superior, inferior, and nasal quadrants.
Conclusions:
- Optic disc size is a significant factor affecting RNFL thickness in POAG.
- Optic disc area may serve as a potential risk factor for glaucomatous optic nerve damage.
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