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Olanzapine as a possible replacement choice for paliperidone-induced Pisa syndrome: a case report
Chang-Chih Tsou1, San-Yuan Huang2
1Resident, Department of Psychiatry, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Objective:
The aim of this paper is to present a case of paliperidone-induced Pisa syndrome and provide treatment experience.
Method:
The case report is combined with a review of the literature.
Results:
A 37-year-old man had been diagnosed with paranoid-type schizophrenia for about 10 years. He received three-month treatment of paliperidone extended release (ER) at 6 mg per day, but showed a progressively Pisa-like physical position. We initially added an anticholinergic drug, but saw no improvement. The paliperidone ER was replaced by olanzapine at 10 mg per day, and the Pisa-like symptom improved after 1 month of the drug replacement.
Conclusions:
We propose olanzapine as a possible replacement choice for patients with paliperidone-related Pisa syndrome.
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