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Updated: Mar 15, 2026

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis
Published on: August 31, 2022
[Radionecrosis after radiation synovectomy]
I Hartig1, I Matveeva2, M Braun2
1Klinik für Rheumatologie, HELIOS Seehospital Sahlenburg, Nordheimstraße 201, 27476, Cuxhaven, Deutschland. ingohartig@gmx.de.
Abstract:
Intra-articular radiation synovectomy is an established and well documented therapy in rheumatology. A rare side effect is necrosis of surrounding tissue caused by leakage of the radionuclide.We describe the case of a 34-year old patient with rheumatoid arthritis who developed skin necrosis 4 weeks after an intra-articular radiation synovectomy of the left wrist. When these lesions are recognized early surgical therapy or hyperbaric oxygen therapy can be initiated.
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