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Long-term effects of adenotonsillectomy in children with obstructive sleep apnoea: protocol for a systematic review

Felipe Damiani1, Gabriel Rada2, Juan Cristóbal Gana3

  • 1Faculty of Medicine, Pontificia Universidad Católica de Chile.

BMJ Open
|September 4, 2016
PubMed

Insights

Adenotonsillar hypertrophy is a key factor in childhood obstructive sleep apnea. Adenotonsillectomy may improve the apnea-hypopnea index, but its long-term benefits require further investigation.

Area of Science:

  • Pediatric Otolaryngology
  • Sleep Medicine
  • Evidence-Based Medicine

Background:

  • Adenotonsillar hypertrophy is the primary anatomical cause of obstructive sleep apnea syndrome in children.
  • The American Academy of Pediatrics endorses adenotonsillectomy as the initial treatment.
  • While adenotonsillectomy can lower the apnea-hypopnea index, its long-term impact is not well-established.

Purpose of the Study:

  • To systematically review the long-term outcomes of adenotonsillectomy in children with obstructive sleep apnea syndrome.
  • To synthesize evidence from randomized controlled trials regarding the efficacy of adenotonsillectomy.

Main Methods:

  • A comprehensive electronic search of MEDLINE, Cochrane CENTRAL, and EMBASE databases.
  • Inclusion of relevant studies by reviewing reference lists, scientific conference proceedings, and ongoing trial registries.
  • Independent data extraction and risk of bias assessment by two researchers, with meta-analyses using RevMan V.5.3 software.

Main Results:

  • Pooled risk ratios and mean differences will be calculated for dichotomous and continuous outcomes, respectively.
  • A random-effects model will be employed for meta-analyses to account for heterogeneity.
  • The study aims to provide a quantitative synthesis of the available evidence.

Conclusions:

  • This systematic review will clarify the long-term effectiveness of adenotonsillectomy for pediatric obstructive sleep apnea syndrome.
  • Findings will inform clinical decision-making regarding surgical intervention for this condition.
  • Dissemination of results through peer-reviewed publications and social networks is planned.
Abstract

Keywords:
ORAL & MAXILLOFACIAL SURGERYSLEEP MEDICINE

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