[Secretion of lysozyme by blood neutrophils during physical exertion]

The effect of physical exercise on the lysozyme release from the blood neutrophils was investigated. The lysozyme RIA was adopted to evaluate its concentration. The RIA main parameters developed on the basis of specific antiserum and 125I-lysozyme, were noted. Physical exercise increased the lysozyme concentration in plasma and decreased it in neutrophils. During 2-hr resting, the partial normalizing of the values occurred. The data obtained suggest the above effect of physical exercise on the neutrophil secretory function to be a mechanism of suppression of the functional neutrophil activity.