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Contemporary Practice Patterns of Voiding Cystourethrography Use at a Large Tertiary Care Center in a Single Payer
Linda C Lee1, Armando J Lorenzo1, Rakan Odeh1
1Division of Urology, Department of Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Insights
Voiding cystourethrogram use declined in children, predating AAP guidelines. A selective approach may increase detection of high-grade vesicoureteral reflux.
Area of Science:
- Pediatric Urology
- Radiology
- Medical Practice Guidelines
Background:
- Voiding cystourethrogram (VCUG) is invasive and involves radiation.
- 2011 American Academy of Pediatrics (AAP) guidelines de-emphasize routine VCUG after initial urinary tract infections in children.
- Trends in VCUG utilization post-guidelines were previously unclear.
Purpose of the Study:
- To examine practice patterns of VCUG use over 8 years.
- To explore the impact of AAP guidelines on VCUG utilization.
- To analyze changes in vesicoureteral reflux detection rates.
Main Methods:
- Retrospective review of VCUGs performed at a pediatric referral center (2008-2015).
- Comparison of initial VCUGs in pre-AAP (2009) and post-AAP (2014) cohorts for patients aged 2-24 months.
- Analysis of vesicoureteral reflux (VUR) detection rates, including high-grade VUR.
Main Results:
- Total annual VCUGs declined during the study period.
- A significant decrease in initial VCUGs was observed post-AAP guidelines (233 in 2009 vs. 95 in 2014).
- While overall VUR detection rates were similar, high-grade VUR detection increased threefold in 2014 compared to 2009 (2.6% vs. 8.4%).
Conclusions:
- VCUG utilization decreased at the institution, starting before 2011.
- The decline in VCUGs cannot be solely attributed to AAP guidelines.
- A selective VCUG approach may be associated with increased detection of high-grade VUR, suggesting a potential benefit.
Purpose:
Voiding cystourethrogram involves radiation exposure and is invasive. Several guidelines, including the 2011 AAP (American Academy of Pediatrics) guidelines, no longer recommend routine voiding cystourethrogram after the initial urinary tract infection in children. The recent trend in voiding cystourethrogram use remains largely unknown. We examined practice patterns of voiding cystourethrogram use and explored the impact of these guidelines in a single payer system in the past 8 years.
Materials And Methods:
We identified all voiding cystourethrograms performed at a large pediatric referral center between January 2008 and December 2015. Patients 2 to 24 months old who underwent an initial voiding cystourethrogram for the diagnosis of a urinary tract infection in the first 6 months of 2009 and 2014 were identified. Medical records were retrospectively reviewed.
Results:
During the study period 8,422 voiding cystourethrograms were performed and the annual number declined over time. In the pre-AAP and post-AAP cohorts 233 and 95 initial voiding cystourethrograms were performed, respectively. While there was no statistically significant difference in the vesicoureteral reflux detection rate between 2009 and 2014 (37.3% vs 43.0%, p = 0.45), there was a threefold increase in high grade vesicoureteral reflux in 2014 (2.6% vs 8.4%, p = 0.03).
Conclusions:
A clear trend toward fewer voiding cystourethrograms was noted at our institution. This decrease started before 2011 and cannot be attributed to the AAP guidelines alone. While most detected vesicoureteral reflux remains low grade, there was a greater detection rate of high grade vesicoureteral reflux in 2014 compared to 2009. This may reflect a favorable impact of a more selective approach to obtaining voiding cystourethrograms.
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