One-Stage Endovascular Embolization for Multiple Intracranial Aneurysms.

Area of Science:

• Neurosurgery
• Interventional Neuroradiology
• Vascular Neurology

Background:

• Multiple intracranial aneurysms pose a higher rupture risk than single aneurysms, complicating clinical management.
• Endovascular embolization offers a less invasive approach to treating complex cerebrovascular conditions.

Purpose of the Study:

• To evaluate the efficacy and safety of one-stage endovascular embolization for treating multiple intracranial aneurysms.

Main Methods:

• A cohort of 33 patients with 72 intracranial aneurysms underwent one-stage endovascular embolization between September 2010 and October 2015.
• Aneurysms were treated with coils (60) or coils with intracranial stents for wide-neck cases (12).
• Outcomes were assessed using modified Rankin Scale (mRS) and digital subtraction angiography (DSA) with follow-up ranging from 3 to 28 months.

Main Results:

• Successful embolization was achieved for all 72 aneurysms without immediate complications.
• Initial DSA showed complete occlusion in 39 aneurysms, neck remnants in 27, and residual aneurysms in six.
• All patients achieved excellent clinical outcomes (mRS 0-1), with no reported ruptures or hemorrhages within six months post-procedure.

Conclusions:

• One-stage endovascular embolization is a safe and effective treatment modality for patients with multiple intracranial aneurysms.
• The procedure demonstrated favorable short-term clinical and angiographic results.
• Long-term outcomes require further investigation to fully establish the durability of this treatment.