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Updated: Mar 15, 2026

A Modified Precipitation Method to Isolate Urinary Exosomes
Published on: January 16, 2015
Advances in the Urinary Exosomes in Renal Diseases
Pei-Pei Chen1, Yan Qin1, Xue-Mei Li1
1Department of Nephrology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
Abstract:
Cells secrete around 30- 100 nm membrane-enclosed vesicles that are released into the extracellular spaceis termed exosomes(EXs). EXs widely present in body fluids and incorporated proteins,nucleic acids that reflect the physiological state of their cells of origin and they may play an important role in cell-to-cell communication in various physiological and disease processes. In this article we review the recent basic and clinical studies in urinary EXs in renal diseases,focusing on their biological characteristics and potential roles as new biological markers,intervention treatment goals,and targeted therapy vectors in renal diseases.However,some issues still exist;in particular,the clinical application of EXs as a liquid biopsy technique warrants further investigations.
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