Localization of 2-glucuronidase in the marginal sinus of rat spleen

The study demonstrated lysosomal 2-glucuronidase activity localized in the marginal sinus epithelium of rat spleen. Immunologically, the marginal sinus is a key structure of the spleen and its enzymatic apparatus differs from that of the cells of the red pulp venous sinuses. The possible physiological significance of this finding is briefly discussed.