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Updated: Mar 15, 2026

The Creation of a Rat Model for Osteosarcopenia via Ovariectomy
Published on: February 21, 2025
[Sarcopenia and functional disability in aged]
Karla Berenice Carrazco-Peña1, Carlos Enrique Tene1, José Del Río-Valdivia1
1Facultad de Medicina, Universidad de Colima, Col., México.
Background:
The significance of sarcopenia in recent years is due to its relationship with functional disability (FD).
Objective:
To determine whether a difference exists in the proportion of sarcopenia in older adults (OA) with different status of FD.
Methods:
Subjects over 65 years of age without sarcopenia associated diseases were included. Overview of the study: 68 OA (24 with and 44 without FD). FD was assessed by Barthel index and clinical battery (stand-up test, grip dynamometry). Sarcopenia was assessed by Lovett-Kendall scale.
Statistical Analysis:
X² and OR (95% CI).
Results:
Sarcopenia was higher in OA with FD (n = 16 of 24 [66.7%] vs. 3 of 44 [6.8%]). The FD was associated with sarcopenia (OR: 27.3; CI: 6-156).
Conclusion:
Sarcopenia is associated with functional dependence in the elderly by testing Kendall-Lovett and with various clinical and functional tools for the detection and diagnosis of FD. The proportion of sarcopenia in OA was higher in the presence of FD.
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