Nocturia
Related Experiment Video
Updated: Mar 15, 2026

Real-Time Void Spot Assay
Published on: February 10, 2023
Mark S Soloway1, Jeffrey P Weiss2, Alan J Wein3
1Memorial Healthcare System, Aventura, FL, USA. mssoloway@yahoo.com.
Abstract:
A 52-year-old man complains of minor urgency and frequency during the day and nocturia × 3-5. His DRE reveals a 30-g benign prostate. He is started on tamsulosin, and his daytime symptoms resolve entirely; however, he still has nocturia × 2-4. He is counseled on lifestyle modifications and to decrease fluid consumption including caffeine but has no improvement in nocturia. Cystoscopy is normal with no evident visual obstruction. A urinalysis is normal. The PVR is 40 ml. He has a normal-sized neck and does not snore. He has no trouble sleeping and awakens because of the urge to void. This is very bothersome.
Related Concept Videos
Sleep-Wake Cycles
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Nightmares and Night Terrors
Nightmares...
Narcolepsy
Regulation of Water Output
Urinary Bladder
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
The Micturition Reflex
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...

