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Homologous Recombination

Homologous Recombination

The basic reaction of homologous recombination (HR) involves two chromatids that contain DNA sequences sharing a significant stretch of identity. One of these sequences uses a strand from another as a template to synthesize DNA in an enzyme-catalyzed reaction. The final product is a novel amalgamation of the two substrates. To ensure an accurate recombination of sequences, HR is restricted to the S and G2 phases of the cell cycle. At these stages, the DNA has been replicated already and the...

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Related Experiment Video

Updated: Mar 15, 2026

Author Spotlight: Development of Simplified CRISPR-Based Tests for Rapid Detection of Infectious Diseases

Author Spotlight: Development of Simplified CRISPR-Based Tests for Rapid Detection of Infectious Diseases

Published on: August 16, 2024

CRISPRdigger: detecting CRISPRs with better direct repeat annotations.

Ruiquan Ge^1,2, Guoqin Mai^1,3, Pu Wang^1,2

¹Shenzhen Institutes of Advanced Technology, and Key Lab for Health Informatics, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China.

Scientific Reports

|September 7, 2016

Summary

This summary is machine-generated.

This study introduces CRISPRdigger, an accurate tool for identifying Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) in prokaryotic genomes. CRISPRdigger improves upon existing methods by recovering more Direct Repeats for better CRISPR annotation accuracy.

Failed At:

2026-06-19T13:37:35.400282+00:00

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