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Updated: Mar 15, 2026
10:37
Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
Published on: November 30, 2016
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[Parasitosis and irritable bowel syndrome]
Catalina Ibarra1, Valentina Herrera1, Edith Pérez de Arce2
1Facultad de Medicina, Universidad de Chile, Chile.
Summary
Irritable bowel syndrome (IBS) may be linked to intestinal parasites. Further research is needed to understand the role of parasitic infections in IBS development, especially in regions with high parasite prevalence.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Epidemiology
Background:
- Irritable bowel syndrome (IBS) is a complex gastrointestinal disorder with multifactorial causes.
- Intestinal parasitic infections are recognized as a potential contributing factor to IBS pathophysiology.
- Post-infection IBS (PI-IBS) develops after acute intestinal infections.
Purpose of the Study:
- To investigate the association between IBS and intestinal parasitic infections in Chile.
- To explore the etiological role of parasites in IBS, considering their high prevalence.
Main Methods:
- Review of existing studies on IBS and intestinal parasitosis.
- Analysis of the association between IBS and specific parasites like Blastocystis hominis, Entamoeba histolytica, and Giardia lamblia.
Main Results:
- A positive association between IBS and Blastocystis hominis infection is well-documented in Chile.
- Globally, amebiasis and giardiasis are also linked to IBS, often transmitted via contaminated food and water.
Conclusions:
- The high prevalence of intestinal parasites in Chile warrants further investigation into their etiological role in IBS.
- Expanding association studies is crucial to clarify the strength of parasitic involvement in IBS.
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