Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.5K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.5K
Glaucoma: Overview01:25

Glaucoma: Overview

1.6K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.6K
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

565
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
565
Computed Tomography01:10

Computed Tomography

9.3K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
9.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characteristics of fall recurrence among persistent, quasi-persistent, and transient fallers: a 3-year analysis from the SCOPE study.

European geriatric medicine·2026
Same author

Authors' Reply to: "Comment on 'Impact of Simultaneous Topography-Guided PRK on Corneal Haze after Cross-Linking for Keratoconus: A Quantitative Densitometry Analysis'".

Cornea·2026
Same author

Efficacy and safety of implantable phakic contact lens versus implantable collamer lens in myopic eyes: a systematic review and meta-analysis.

Journal of cataract and refractive surgery·2026
Same author

Safety and tolerability of switching to bictegravir/emtricitabine/tenofovir alafenamide versus continuing dolutegravir/lamivudine in people living with HIV with neuropsychiatric comorbidities: Week 24 and 48 results from the Management of INSTI-associated Neuropsychiatric Disorders (MIND) clinical trial.

International journal of antimicrobial agents·2026
Same author

Point-of-Care Ultrasound in Blunt Chest Trauma: Diagnostic Performance and Clinical Relevance.

Cureus·2026
Same author

Sustainable Production of Poly(3-hydroxybutyrate) Using Eucalyptus Bark: Integration with Green Downstream Processing.

ACS sustainable chemistry & engineering·2026

Related Experiment Video

Updated: Mar 15, 2026

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.9K

Corneal Elevation Topography in Primary Open Angle Glaucoma.

Pedro Gil1, Joana Pires, Rita Matos

  • 1Centro Hospitalar Baixo Vouga, Aveiro, Portugal.

Journal of Glaucoma
|September 7, 2016
PubMed
Summary
This summary is machine-generated.

Primary open angle glaucoma patients show forward shifting of corneal surfaces, linked to disease severity. This corneal topography change may help monitor glaucoma progression.

More Related Videos

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.9K
Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
09:03

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Published on: June 20, 2015

10.5K

Related Experiment Videos

Last Updated: Mar 15, 2026

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.9K
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.9K
Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
09:03

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Published on: June 20, 2015

10.5K

Area of Science:

  • Ophthalmology
  • Corneal topography
  • Glaucoma research

Background:

  • Primary open angle glaucoma (POAG) is a leading cause of irreversible blindness.
  • Understanding corneal structural changes in POAG is crucial for diagnosis and management.

Purpose of the Study:

  • To compare anterior and posterior corneal topographic elevation maps in POAG patients and healthy controls.
  • To correlate corneal topography findings with glaucoma functional damage staging.

Main Methods:

  • Utilized Pentacam HR corneal topography on 111 POAG patients and 106 healthy controls.
  • Analyzed mean anterior keratometry and anterior/posterior elevation maps (3, 5, 7 mm zones).
  • Classified glaucoma severity using the Glaucoma Staging System (GSS) based on Humphrey visual field results.

Main Results:

  • POAG patients exhibited significantly higher maximum elevation readings in both anterior and posterior corneal maps across central 5 mm and 7 mm zones compared to controls.
  • Weak but significant correlations were found between GSS stage and maximum anterior/posterior elevation measurements.
  • Age and central corneal pachymetry were similar between POAG patients and controls.

Conclusions:

  • POAG is associated with a forward shift in both anterior and posterior corneal surfaces.
  • This corneal structural change correlates with advanced glaucoma functional damage.
  • Corneal topography may serve as a potential biomarker for monitoring POAG progression.