Phospholipids of liver cell nuclei during hibernation of Yakutian ground squirrel
Related Experiment Video
Updated: Mar 15, 2026

Lipid Exchange Assay in Living Cells
Published on: March 21, 2025
A A Lakhina1, L N Markevich2, N M Zakharova2
1Institute of Cell Biophysics, Russian Academy of Sciences, ul. Institutskaya 2, Pushchino, Moscow oblast, 142290, Russia. ikolomizeva2@yandex.ru.
Abstract:
In hibernating Yakutian ground squirrels S. undulatus, the content of total phospholipids in the nuclei of liver increased by 40% compared to that in animals in summer. In torpid state, the amount of sphingomyelin increased almost 8 times; phosphatidylserine, 7 times; and cardiolipin, 4 times. In active "winter" ground squirrels, the amount of sphingomyelin, phosphatidylserine, and cardiolipin decreased compared to the hibernating individuals but remained high compared to the "summer" ones. The torpor state did not affect the amount of lysophosphatidylcholine and phosphatidylinositol.
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