Related Experiment Video
Updated: Mar 15, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
Published on: May 16, 2025
Evolution over thirty years of the profile of inpatients with reactive arthritis in a tertiary rheumatology unit
Anne Brinster1, Xavier Guillot1, Clément Prati1
1Service de Rhumatologie, CHRU de Besançon and Université de Franche-Comté, Besançon, France.
Abstract:
Reactive arthritis (ReA) is sterile arthritis occurring after extra articular bacterial infection. The aim of this study was to analyze, over 30 years, clinical, biological and imaging characteristics as well as therapeutic management of new cases of ReA, comparing two periods.
Methods:
retrospective monocentric study, data of all the patients followed in our unit between January 1st 1984 and April 2014 with the diagnosis or ReA were analyzed (clinical and biological features, management and outcome), and compared between two periods: from January 1984 to December 1993, and from January 2004 to December 2013.
Results:
Sixty two patients fulfilling international diagnosis criteria were analyzed. There was no significant difference between the two periods in number of new cases, clinical presentation, biological data or outcome. Changes in therapeutic management were obvious with occurrence of anti TNF in the recent period.
Conclusion:
Reactive arthritis is still a current rheumatologic problem in a developed country, with a need of early and tailored rheumatologic management.
Insights
Reactive arthritis (ReA) remains a significant rheumatologic issue. While clinical features and outcomes haven't changed over 30 years, modern treatments now include anti-TNF therapies.
Area of Science:
- Rheumatology
- Immunology
- Infectious Diseases
Background:
- Reactive arthritis (ReA) is a sterile joint inflammation following an extra-articular bacterial infection.
- Understanding the long-term clinical and therapeutic evolution of ReA is crucial for patient management.
Purpose of the Study:
- To analyze clinical, biological, and imaging characteristics of new Reactive Arthritis (ReA) cases over 30 years.
- To compare therapeutic management strategies for ReA between two distinct time periods.
Main Methods:
- A retrospective monocentric study analyzing data from 1984 to 2014.
- Comparison of patient data from two periods: 1984-1993 and 2004-2013.
Main Results:
- Sixty-two patients meeting international ReA diagnostic criteria were analyzed.
- No significant differences were observed in new case numbers, clinical presentation, biological data, or outcomes between the two periods.
- Therapeutic management evolved, with the introduction of anti-TNF agents in the more recent period.
Conclusions:
- Reactive arthritis continues to be a relevant rheumatologic concern in developed countries.
- Early and individualized rheumatologic management is essential for effective ReA treatment.
More Related Videos
Related Concept Videos
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Rheumatic Heart Disease I: Introduction
Rheumatic Heart Disease IV: Nursing Management
Rheumatic Heart Disease III: Medical Management
Acute Pyelonephritis II: Diagnostic Studies and Management

