Evolution over thirty years of the profile of inpatients with reactive arthritis in a tertiary rheumatology unit

Anne Brinster1, Xavier Guillot1, Clément Prati1

  • 1Service de Rhumatologie, CHRU de Besançon and Université de Franche-Comté, Besançon, France.

Reumatologia Clinica
|September 8, 2016
PubMed

Insights

Reactive arthritis (ReA) remains a significant rheumatologic issue. While clinical features and outcomes haven't changed over 30 years, modern treatments now include anti-TNF therapies.

Area of Science:

  • Rheumatology
  • Immunology
  • Infectious Diseases

Background:

  • Reactive arthritis (ReA) is a sterile joint inflammation following an extra-articular bacterial infection.
  • Understanding the long-term clinical and therapeutic evolution of ReA is crucial for patient management.

Purpose of the Study:

  • To analyze clinical, biological, and imaging characteristics of new Reactive Arthritis (ReA) cases over 30 years.
  • To compare therapeutic management strategies for ReA between two distinct time periods.

Main Methods:

  • A retrospective monocentric study analyzing data from 1984 to 2014.
  • Comparison of patient data from two periods: 1984-1993 and 2004-2013.

Main Results:

  • Sixty-two patients meeting international ReA diagnostic criteria were analyzed.
  • No significant differences were observed in new case numbers, clinical presentation, biological data, or outcomes between the two periods.
  • Therapeutic management evolved, with the introduction of anti-TNF agents in the more recent period.

Conclusions:

  • Reactive arthritis continues to be a relevant rheumatologic concern in developed countries.
  • Early and individualized rheumatologic management is essential for effective ReA treatment.

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