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Metastatic lesions: A diagnostic dilemma-retrospective study, Srinagar, Jammu and Kashmir, India
Summyia Farooq1, Afreen Nadaf2, Ambreen Beigh1
1Department of Pathology, GMC, Srinagar, Jammu and Kashmir, India.
Background:
Renal clear cell carcinoma (RCC) accounts for about 3% of adult malignancies and about 90% of neoplasms of the kidney. It is most common in men aged 50 to 60 years old. RCC has different manifestations, including metastasis in uncommon sites and paraneoplastic syndromes.
Aims:
To evaluate the clinicopathological pattern of RCC.
Materials And Methods:
This study was conducted in the Department of Pathology, Government Medical College, Srinagar. It was a retrospective study done over a period of 5 years, November 2009 to November 2014.
Results:
The study was done to evaluate the clinicopathological pattern of 6 cases of RCC diagnosed at a tertiary care hospital. All patients were males, presenting with submandibular swellings without any other symptom. Radiological and histopathological examination proved the lesion as metastasis of renal cell carcinoma to the mandible.
Conclusion:
Being a rare presentation in the head and neck region, metastatic renal cell carcinoma needs to be considered in the differential diagnosis of submandibular swellings even in patients younger than 40 years.
Insights
Metastatic renal cell carcinoma (RCC) rarely presents as submandibular swelling in males. This study highlights the importance of considering metastatic RCC in the differential diagnosis of such head and neck masses.
Area of Science:
- Oncology
- Pathology
- Urology
Background:
- Renal clear cell carcinoma (RCC) comprises 90% of kidney neoplasms and 3% of adult malignancies.
- Typically affects men aged 50-60, with varied presentations including metastasis and paraneoplastic syndromes.
Purpose of the Study:
- To evaluate the clinicopathological pattern of renal clear cell carcinoma (RCC).
Main Methods:
- Retrospective analysis of 6 RCC cases diagnosed between November 2009 and November 2014.
- Involved radiological and histopathological examination of diagnosed lesions.
Main Results:
- All 6 diagnosed cases were male patients presenting with submandibular swellings.
- Radiological and histopathological findings confirmed metastatic renal cell carcinoma to the mandible.
Conclusions:
- Metastatic renal cell carcinoma (RCC) is a rare cause of head and neck masses.
- Consider metastatic RCC in the differential diagnosis of submandibular swellings, even in younger patients (<40 years).
