Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The silent trajectory: unaddressed adolescent arecanut chewing and early onset of oral submucous fibrosis.

International journal of adolescent medicine and health·2026

Same author

Immunomodulatory mediators IL-33, soluble ST2, IL-10, IFN-<i>γ</i> in the serum of patients with oral potentially malignant disorders and oral squamous cell carcinoma.

Frontiers in oral health·2026

Same author

Evaluation of Platelet-Rich Plasma as an Adjunct to Closed Reduction of Unilateral Condylar Fractures of Mandible.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons·2025

Same author

Use of Prolene Mesh in the Treatment of Traumatic Midface Fractures.

Journal of long-term effects of medical implants·2025

Same author

From resection to reconstruction: patient-specific temporomandibular joint replacement in patients with ameloblastomas - a report of three cases.

Journal of the Korean Association of Oral and Maxillofacial Surgeons·2025

Same author

The clinicopathological implications of serum IL-33 and sST2 as cancer biomarkers: A narrative review.

Journal of oral biology and craniofacial research·2025

Search research articles

Related Experiment Video

Updated: Mar 15, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

Pseudolymphoma versus lymphoma: An important diagnostic decision.

Sujeeth Kumar Shetty¹, Usha Hegde², Leka Jagadish³

¹Department of Oral and Maxillo Facial Surgery, JSS Dental College and Hospital, Mysuru, Karnataka, India.

Journal of Oral and Maxillofacial Pathology : JOMFP

|September 8, 2016

Summary

This study presents a case of lymphocytoma cutis, a benign skin condition that can mimic malignancy. Accurate diagnosis requires careful clinical and histopathological evaluation to differentiate it from cancerous growths.

Keywords:

Cutaneous lymphoma polyclonality pseudolymphoma reactive lesion

More Related Videos

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma

Published on: January 9, 2019

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Published on: June 10, 2025

Related Experiment Videos

Last Updated: Mar 15, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma

Published on: January 9, 2019

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Published on: June 10, 2025

Area of Science:

Dermatopathology
Oncology
Immunohistochemistry

Background:

Distinguishing benign skin lesions from malignant ones is crucial for appropriate patient management and prognosis.
Some benign inflammatory conditions, like lymphocytoma cutis, can present with features that mimic cutaneous lymphomas.
Accurate histopathological and immunohistochemical analysis is essential for definitive diagnosis.

Observation:

Lymphocytoma cutis, also known as Spiegler-Fendt Sarcoid, is a type of pseudolymphoma characterized by lymphocyte accumulation in the skin.
This condition can clinically and histopathologically resemble malignant cutaneous lymphomas.
The presented case involves a seemingly minor facial growth that mimicked a more serious condition.

Findings:

The case highlights the diagnostic challenges posed by pseudolymphomas that resemble malignancies.
Comprehensive evaluation including clinical assessment and specialized laboratory tests is necessary.
Histopathological and immunohistochemical examinations are key to correctly identifying lymphocytoma cutis.

Implications:

Correctly diagnosing lymphocytoma cutis prevents unnecessary aggressive treatments for malignancy.
Understanding these mimics improves diagnostic accuracy in dermatopathology.
This case underscores the importance of a multidisciplinary approach in diagnosing complex skin lesions.