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Juvenile nasopharyngeal angiofibroma
Jashika Adil Shroff Makhasana1, Meena A Kulkarni2, Suhas Vaze3
1Department of Oral Pathology and Microbiology, Terna Dental College and Hospital, Navi Mumbai, Maharashtra, India.
Journal of Oral and Maxillofacial Pathology : JOMFP
|September 8, 2016
Summary
Juvenile nasopharyngeal angiofibroma (JNA) is a rare, aggressive tumor in adolescent males. This case report highlights a rare intra-oral JNA manifestation, emphasizing early diagnosis and treatment for better management.
Area of Science:
- Otolaryngology
- Pathology
- Radiology
Background:
- Juvenile nasopharyngeal angiofibroma (JNA) is a rare, benign neoplasm originating in the nasopharynx.
- It predominantly affects adolescent males and is known for aggressive local invasion.
Observation:
- Painless, progressive unilateral nasal obstruction, epistaxis, and rhinorrhea are common presenting symptoms.
- Diagnosis involves clinical history, examination, endoscopy, and advanced imaging (CT, MRI, arteriography).
- Histopathology shows a fibrocellular stroma with spindle cells, collagen, and irregular vascularity.
Findings:
- This article presents a case of JNA with an unusual intra-oral manifestation in a 17-year-old male.
- The tumor demonstrated aggressive local spread, extending towards the skull base and cranium.
Implications:
- Early diagnosis, accurate staging, and comprehensive treatment are crucial for managing JNA.
- Understanding rare presentations like intra-oral JNA is vital for effective patient care and preventing recurrence.
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