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B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical
Tabita Joy Chettiankandy1, Jagdish Vishnu Tupkari2, Keshav Kumar2
1Department of Oral Pathology, Government Dental College and Hospital, Mumbai, Maharashtra, India.
Abstract:
B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma (DLBCL) and classical Burkitt's lymphoma (BL), is a diagnostic provisional category in the World Health Organization 2008 classification of lymphomas. This category was designed as a measure to accommodate borderline cases that cannot be reliably classified into a single distinct disease entity after all available morphological, immunophenotypical and molecular studies have been performed. Typically, these cases share features intermediate between DLBCL and classical BL or include characteristics of both lymphomas. The rarity of such cases poses a tremendous challenge to both pathologists and oncologists because its differential diagnosis has direct implications for management strategies. In this article, we present a "classical unclassifiable lymphoma with features intermediate between DLBCL and BL" in a young male patient and review of literature.
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