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Updated: Mar 15, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Metabolic syndrome as a risk indicator for periodontal disease and tooth loss
Marta L Musskopf1,2, Luciana D Daudt3, Patrícia Weidlich3
1Department of Periodontology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil. martalmusskopf@gmail.com.
Objectives:
The aim of the present study was to evaluate the association of metabolic syndrome (MS) with periodontitis (PE) and tooth loss (TL).
Materials And Methods:
A cross-sectional study was conducted with 363 individuals who underwent full-mouth periodontal examination, and the association between MS and PE was evaluated considering three outcomes: severe periodontitis, mean probing depth ≥2.4 mm, and mean clinical attachment loss ≥2.0 mm. The prevalence ratio (PR) between MS and PE was calculated using a model adjusted for gender, age, smoking, years of education, and socioeconomic status.
Results:
The adjusted model showed a PR for severe periodontitis of 1.17 (95 % CI 0.83-1.65). There was no significant association between MS and PE defined as mean probing depth ≥2.4 mm. MS was significantly associated with PE defined as mean attachment loss ≥2 mm in individuals aged 41-60 years (PR 1.47, 95 % CI 1.05-2.06). In addition, MS was associated with TL (>6 teeth) (PR 1.23, 95 % CI 1.02-1.49) for all ages, both in crude and adjusted analyses.
Conclusions:
We concluded that there is a weak association of MS with both attachment loss and TL.
Clinical Relevance:
Patients with MS seem to have a higher risk of attachment loss and tooth loss and should be screened for periodontal disease.
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