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Related Concept Videos

Vaccinations01:51

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
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Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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Vaccines and multiple sclerosis: a systematic review.

Mia Topsøe Mailand1, Jette Lautrup Frederiksen2

  • 1University of Copenhagen, Copenhagen, Denmark.

Journal of Neurology
|September 9, 2016
PubMed
Summary

Vaccinations against various diseases, including hepatitis B and MMR, do not increase the risk of developing multiple sclerosis (MS) or MS relapse. Further research is needed for BCG, tetanus, and diphtheria vaccines.

Keywords:
ImmunizationMultiple sclerosisVaccination

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Area of Science:

  • Neurology
  • Immunology
  • Public Health

Background:

  • Vaccinations are crucial for disease prevention.
  • Concerns exist regarding potential links between vaccines and neurological conditions like multiple sclerosis (MS).

Purpose of the Study:

  • To systematically review the scientific literature on the association between vaccinations and the risk of developing MS.
  • To evaluate the impact of vaccinations on MS relapse rates.

Main Methods:

  • A systematic literature review was conducted.
  • The PubMed database was searched for relevant studies.

Main Results:

  • No increased risk of developing MS was found following vaccination against hepatitis B virus, human papillomavirus, seasonal influenza, measles-mumps-rubella, variola, tetanus, Bacillus Calmette-Guérin (BCG), polio, or diphtheria.
  • No increased risk of MS relapse was observed after influenza vaccination.

Conclusions:

  • Current evidence suggests no causal link between common vaccinations and MS development or relapse.
  • Further investigation is warranted for the therapeutic potential of BCG and preventive potential of tetanus and diphtheria vaccines in MS.