Background review for the 2016 European guideline on Mycoplasma genitalium infections

J S Jensen1, M Cusini2, M Gomberg3

  • 1Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark. jsj@ssi.dk.

Insights

Mycoplasma genitalium causes a significant portion of non-gonococcal urethritis in men and women, and is linked to pelvic inflammatory disease. This review details the 2016 European guideline for managing M. genitalium infections.

Area of Science:

  • Sexually Transmitted Infections
  • Microbiology
  • Public Health

Background:

  • Mycoplasma genitalium is a common cause of urethritis in men and cervicitis/pelvic inflammatory disease (PID) in women.
  • Transmission occurs via direct mucosal contact, with frequent asymptomatic infections.
  • Symptoms vary, including discharge, dysuria, abdominal pain, and dyspareunia.

Purpose of the Study:

  • To present the evidence supporting the 2016 European guideline for Mycoplasma genitalium infections.
  • To outline recommendations for diagnosis, treatment, and patient management.
  • To consolidate expert consensus from multiple European societies.

Main Methods:

  • Review of evidence base for the 2016 European guideline.
  • Synthesis of recommendations from contributing European organizations.
  • Inclusion of input from public health bodies like ECDC and WHO.

Main Results:

  • The guideline addresses indications for testing, diagnostic methods, and treatment strategies.
  • It provides a framework for managing M. genitalium infections in clinical practice.
  • Evidence supports specific diagnostic and therapeutic approaches.

Conclusions:

  • The 2016 European guideline offers comprehensive recommendations for Mycoplasma genitalium.
  • Adherence to the guideline is crucial for effective patient management and control.
  • The guideline reflects a collaborative effort by leading European medical societies.

Related Concept Videos

Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
1.5K
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
386
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
594
Urinary Tract Infection I: Introduction01:26

Urinary Tract Infection I: Introduction

Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
916
Bacterial Phylum Tenericutes01:24

Bacterial Phylum Tenericutes

The phylum Tenericutes, which includes the single class Mollicutes, comprises bacteria that lack cell walls. The term "Mollicutes" derives from the Latin word mollis, meaning "soft." These organisms are among the smallest known and are commonly referred to as mycoplasmas due to the prominence of the genus Mycoplasma, which includes well-known human pathogens. Despite their inability to stain gram-positively (a result of their lack of cell walls), mycoplasmas are phylogenetically related to the...
571
Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
1.0K