Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vision01:24

Vision

61.2K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
61.2K
Association Areas of the Cortex01:21

Association Areas of the Cortex

10.3K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
10.3K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

8.8K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
8.8K
Diencephalon: Thalamus and Information Relay01:27

Diencephalon: Thalamus and Information Relay

5.3K
The thalamus, often called “the gateway to the cerebral cortex,” is vital in processing and directing sensory and motor signals throughout the brain. Almost all inputs destined for the cerebral cortex, except for olfactory signals, are relayed through the thalamus. The thalamus is  a sophisticated relay station, channeling information from various brain regions to the cerebral cortex, as well as a filter, prioritizing certain signals over others based on current physiological...
5.3K
Parallel Processing01:20

Parallel Processing

857
The brain processes sensory information rapidly due to parallel processing, which involves sending data across multiple neural pathways at the same time. This method allows the brain to manage various sensory qualities, such as shapes, colors, movements, and locations, all concurrently. For instance, when observing a forest landscape, the brain simultaneously processes the movement of leaves, the shapes of trees, the depth between them, and the various shades of green. This enables a quick and...
857
Visual System01:26

Visual System

2.2K
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Myelin dystrophy impairs signal transmission and working memory in a multiscale model of the aging prefrontal cortex.

eLife·2024
Same author

Susceptibility to Low Vitamin B6 Diet-induced Gestational Diabetes Is Modulated by Strain Differences in Mice.

Endocrinology·2023
Same author

Flexible integration of continuous sensory evidence in perceptual estimation tasks.

Proceedings of the National Academy of Sciences of the United States of America·2022
Same author

Evaluating the Effects of BPA and TBBPA Exposure on Pregnancy Loss and Maternal-Fetal Immune Cells in Mice.

Environmental health perspectives·2022
Same author

Flexible categorization in perceptual decision making.

Nature communications·2021
Same author

Identification of the novel Ido1 imprinted locus and its potential epigenetic role in pregnancy loss.

Human molecular genetics·2018

Related Experiment Video

Updated: Mar 15, 2026

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings
07:08

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings

Published on: August 1, 2018

8.8K

Prefrontal Neurons Represent Motion Signals from Across the Visual Field But for Memory-Guided Comparisons Depend on

Klaus Wimmer1, Philip Spinelli2, Tatiana Pasternak3

  • 1Institut d'Investigacions Biomèdiques August Pi i Sunyer 08036 Barcelona, Spain, and.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|September 9, 2016
PubMed
Summary

The lateral prefrontal cortex (LPFC) integrates visual motion information from both hemispheres for decision-making. However, successful comparisons of visual motion require stimuli to appear at the same retinal location, highlighting the role of localized neurons.

Keywords:
direction selectivityhemifieldsworking memory

More Related Videos

Simultaneous Eye Tracking and Single-Neuron Recordings in Human Epilepsy Patients
07:43

Simultaneous Eye Tracking and Single-Neuron Recordings in Human Epilepsy Patients

Published on: June 17, 2019

8.4K
Eye Movement Monitoring of Memory
08:06

Eye Movement Monitoring of Memory

Published on: August 15, 2010

15.3K

Related Experiment Videos

Last Updated: Mar 15, 2026

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings
07:08

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings

Published on: August 1, 2018

8.8K
Simultaneous Eye Tracking and Single-Neuron Recordings in Human Epilepsy Patients
07:43

Simultaneous Eye Tracking and Single-Neuron Recordings in Human Epilepsy Patients

Published on: June 17, 2019

8.4K
Eye Movement Monitoring of Memory
08:06

Eye Movement Monitoring of Memory

Published on: August 15, 2010

15.3K

Area of Science:

  • Neuroscience
  • Cognitive Science

Background:

  • Visual decisions often involve comparing sequential stimuli presented across the visual field.
  • The lateral prefrontal cortex (LPFC) plays a key role in these comparisons, receiving asymmetric sensory input from contralateral and ipsilateral visual stimuli.

Purpose of the Study:

  • To investigate how the LPFC integrates visual motion information from both hemispheres during memory-guided comparisons.
  • To determine the role of LPFC neuronal activity and receptive field properties in visual motion comparison.

Main Methods:

  • Electrophysiological recordings from LPFC neurons in nonhuman primates.
  • Analysis of neuronal responses to visual motion stimuli presented in different hemifields.
  • Investigating the impact of stimulus location on comparison-related neuronal activity.

Main Results:

  • LPFC neurons carry similar signals about motion direction for both contralateral and ipsilateral stimuli, despite differences in response latency and strength.
  • Neuronal responses reflect the remembered stimulus direction during the comparison phase.
  • Comparison effects in the LPFC are strictly dependent on the spatial overlap of stimuli at the same retinal location.

Conclusions:

  • The LPFC effectively incorporates visual motion information from both hemispheres.
  • The comparison process relies on interactions with sensory neurons possessing localized receptive fields.
  • Successful visual decisions depend on the coordinated activity between the LPFC and sensory neurons during stimulus comparison.