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Related Concept Videos

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Next-generation Sequencing

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The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
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DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
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RNA-seq03:21

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
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Related Experiment Video

Updated: Mar 15, 2026

Sequencing of mRNA from Whole Blood using Nanopore Sequencing
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Nanopore Technology: A Simple, Inexpensive, Futuristic Technology for DNA Sequencing.

P D Gupta1

  • 1Manipal University, Manipal, Karnataka India.

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|September 9, 2016
PubMed
Summary

DNA sequencing is crucial in healthcare, but traditional methods are slow and costly. Nanopore sequencing offers a simple, fast, and affordable alternative, representing the future of DNA analysis.

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Area of Science:

  • Biotechnology
  • Genomics
  • Molecular Biology

Background:

  • The established importance of DNA sequencing in healthcare necessitates efficient methodologies.
  • Sanger's Capillary Electrophoresis DNA sequencing, while foundational, presents challenges in terms of time, complexity, and cost.

Discussion:

  • The increasing accessibility and versatility of DNA sequencing demand simpler, faster, and more economical technologies.
  • Nanopore DNA sequencing technology emerged in the early 21st century as a response to these evolving needs.

Key Insights:

  • Traditional DNA sequencing methods like Sanger's are time-consuming and expensive.
  • Nanopore sequencing technology is a developing but promising alternative for accessible DNA analysis.

Outlook:

  • Despite being in its early stages, Nanopore DNA sequencing is positioned as a futuristic technology.
  • Advancements in Nanopore technology are expected to further revolutionize DNA sequencing accessibility and application.